Tretinoin (topical Vitamin A) was originally developed as an acne cream and was also noted to help sun damaged skin, fine wrinkling, mottled hyperpigmentation and skin roughness. In addition to clinical improvement of skin, numerous microscopic changes are noted such as improvement or reversal of ultraviolet radiation induced changes, normalization of cell architecture, formation of new collagen, and formation of new blood vessels.

Make sure your face is completely dry and then apply a thin layer as prescribed then wash your hands. A little goes a long way and using more will not quicken the results. In the first seven to 10 days, your acne may get worse. The normal side effects like flaking, irritation, and redness will usually start to diminish after a couple or weeks of use.

Tretinoin is also a very important part of the Obagi Nu-Derm Skin Care Regimen. Remember, Tretinoin will make you more susceptible to the sun so an SPF 30 broad spectrum sunscreen is recommended. Note: It may take six to nine weeks to see a noticeable difference.